Vindicate synonyms, vindicate pronunciation, vindicate translation, english dictionary definition of vindicate. Vindicate means to justify, prove, or reinforce an idea or to absolve from guilt. If your family thinks you hogged the last piece of pie on thanksgiving,.
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Vindicate somebody to prove that somebody is not guilty when they have been accused of doing something wrong or illegal; To prove that what someone said or did was right or true, after other people thought it was.